Can Fibroids Come Back After UFE? What the Research Shows

Aug 18, 2026

Can Fibroids Come Back After UFE? What the Research Shows

If you are dealing with heavy menstrual bleeding, severe pelvic pain, or a constant feeling of pressure in your lower abdomen, you already know how deeply uterine fibroids can disrupt your daily life. Many women spend years tolerating these debilitating symptoms because they are led to believe the only permanent solution is a hysterectomy. Understandably, the prospect of major surgery—complete with a lengthy hospital stay, a painful recovery period, and the loss of your uterus—is daunting. You want true relief, but you also want a non-surgical alternative that actually works and lasts.

This is where Uterine Fibroid Embolization (UFE) comes in. UFE is a minimally invasive, outpatient procedure designed to treat fibroids safely without removing the uterus. But when women discover this alternative, one of the most pressing questions they have is: Will my fibroids just come back? It is a completely fair question. When you invest time and hope into a medical treatment, you deserve to know what the long-term reality looks like. Let us dive into what clinical research actually shows about UFE, how the procedure targets fibroids, and what you can expect for your future health.

How UFE Treats Fibroids Without Surgery

To understand whether fibroids can return, you first need to understand exactly how Uterine Fibroid Embolization works. At MIVA Medical, Dr. Silas Williams, our Director of Women’s Health, regularly performs this highly effective procedure to help patients get their lives back on track without the need for an operating room.

Interventional radiologist explaining the non-surgical Uterine Fibroid Embolization procedure to a female patient in a bright consultation room
UFE targets the blood supply of fibroids, providing a non-surgical alternative to a hysterectomy.

Unlike a myomectomy (which surgically cuts the fibroids out) or a hysterectomy (which removes the entire uterus), UFE tackles the problem at its core: the blood supply. Fibroids are benign, living tumors that require a steady flow of nutrient-rich, oxygenated blood to survive and grow. During a UFE procedure, a specialized interventional radiologist uses advanced imaging to guide a tiny catheter into the uterine arteries. Microscopic particles are then released to safely block the blood flow feeding the fibroids.

Starved of their blood supply, the treated fibroids begin to shrink and soften immediately. Over the next several weeks and months, they wither into harmless scar tissue. Because the procedure is highly targeted, the healthy surrounding uterine tissue continues to receive an adequate blood supply from alternative pathways, preserving the organ entirely. Since UFE is a true outpatient procedure, patients typically go home the exact same day with just a small bandage, completely avoiding the lengthy, painful recovery associated with traditional surgical interventions.

What the Clinical Research Says About Fibroid Recurrence

When patients ask if fibroids can come back, the answer requires a careful medical distinction between treated fibroids and new fibroids. The clinical data surrounding UFE is extensive, well-established, and highly encouraging for women seeking long-term symptom relief.

According to decades of medical literature, UFE has a remarkable overall success rate, ranging from 85% to 90% for the effective relief of heavy bleeding and severe pelvic pressure. But what happens to those targeted fibroids after five or ten years have passed?

💡 Clinical Fact: Research consistently shows that once a specific fibroid has been successfully embolized and its blood supply completely cut off, that specific fibroid dies. It does not magically regenerate or “come back to life.”

However, because UFE beautifully preserves the uterus, your body still retains the biological environment that created fibroids in the first place. Therefore, it is clinically possible for brand new fibroids to form in the future, particularly if you are several years away from menopause. The younger a woman is when she undergoes UFE (or any fibroid-sparing treatment like a myomectomy), the longer her window of time for new fibroids to potentially develop.

That being said, the long-term recurrence rates of symptoms after UFE are quite low. Most medical studies suggest that only a small percentage of women will ever need a secondary intervention within five to ten years. For the vast majority, UFE provides permanent, life-changing symptom relief that carries them comfortably through to natural menopause, when estrogen levels drop and the risk of fibroid growth vanishes completely.

New Fibroids vs. Treated Fibroids: A Crucial Difference

When discussing the potential for recurrence, it is vital to separate medical myths from reality. Here is how you can think about the long-term outcomes of UFE versus traditional surgical methods:

Treated Fibroids Die

Once the blood flow is safely stopped via embolization, the fibroid shrinks, calcifies, and turns into scar tissue. It cannot regrow or cause future issues.

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New Growth is Possible

Because your uterus remains intact, new fibroids can technically form over time, though this is a gradual process and does not happen to everyone.

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Menopause is the Finish Line

Fibroids are fueled by estrogen. Once you reach natural menopause, new fibroids stop forming entirely, and any existing ones naturally shrink away.

Common Questions About Life After Uterine Fibroid Embolization

Healthy, happy woman standing outdoors, smiling comfortably after experiencing successful relief from symptomatic uterine fibroids
Many women find lasting, permanent relief from heavy bleeding and pelvic pain after UFE.

It is completely normal to have questions when planning for your long-term health and wellness. Here are a few common concerns patients bring up during consultations at our Independence clinic:

If I get new fibroids, can I have UFE again?

Yes. In the rare event that new fibroids develop years later and begin causing problematic symptoms, UFE can often be safely repeated. Unlike traditional surgery, which creates significant abdominal scar tissue that makes repeat operations increasingly risky, embolization leaves your anatomical structure fully intact and easily accessible.

How does UFE compare to a myomectomy for recurrence?

A myomectomy is a surgical procedure that manually cuts out existing fibroids. Interestingly, clinical research indicates that the risk of new fibroids growing after a myomectomy is comparable to—and in some major studies, slightly higher than—the risk of new fibroids forming after UFE. Both procedures leave the uterus safely in place, but UFE successfully avoids surgical trauma, deep incisions, and lengthy hospital stays.

Will my treated fibroids pass out of my body?

While a very small percentage of women may experience fibroid expulsion (where a fibroid located near the inner uterine lining breaks down and passes safely through the vagina), the vast majority of treated fibroids simply shrink inside the body. They remain safely embedded in the uterine wall as harmless, completely asymptomatic scar tissue for the rest of your life.

Why Choose MIVA Medical for Your Non-Surgical Treatment?

Living with the debilitating pain and unpredictable bleeding of uterine fibroids can drain your energy, dictate your schedule, and rob you of your confidence. But you do not have to settle for invasive surgery just to get your life back. At MIVA Medical, proudly serving the greater Kansas City metro area—including Independence, Lee’s Summit, Blue Springs, and Overland Park—we specialize exclusively in advanced, minimally invasive therapies.

Dr. Silas Williams and our compassionate clinical team are dedicated to providing medical solutions that fiercely prioritize your comfort, safety, and rapid recovery. We perform Uterine Fibroid Embolization right here in our modern outpatient center, meaning you avoid the sprawling hospital system entirely. You will receive highly personalized care, honest answers about your specific condition, and a treatment plan tailored precisely to your unique anatomy. We firmly believe that every woman deserves the opportunity to make an informed, confident decision about her own body.

Take the First Step Toward Lasting Relief

If you are tired of living with heavy bleeding and pelvic pain, Uterine Fibroid Embolization could be the permanent, non-surgical answer you have been searching for. You do not have to navigate this journey alone, and you certainly do not have to accept a hysterectomy as your only option. Learn more about how Uterine Fibroid Embolization can help you reclaim your comfort.

Book a Consultation Today